The formation on the gRNA dimer is mediated by a 'kissing' interaction between the DIS hairpin loops of the gRNA monomers. Concurrently, specific guanosine residues inside the gRNA are made available for binding of the nucleocapsid (NC) protein resulting in the subsequent virion assembly.[seventy one] The labile gRNA dimer has https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/